
Confluence Labs
AI models that learn from experience
While modern AI excels in any area you can collect a lot of data for, it struggles in areas where data is sparse or costly to attain. Designing new molecules, discovering new physics, and engineering new materials are all domains where collecting data is extremely costly. We dream of a world where AI accelerates research in all of these domains and creates a more abundant future for humanity, but the current technology is not there. That’s why we started Confluence Labs. We are building AI that can design highly effective experiments in data-sparse domains and learn maximally from the data it already has.
- Website
- confluence.sh
- City
- San Francisco
- Country
- United States
- YC batch
- Winter 2026
- Team
- 2 people
- Stage
- Early stage
- AI-native
- Yes
More AI & models in San Francisco

AnthropicLab$965bnMafia
Safety-focused lab building the Claude models.
OpenAILab$852bn
Frontier model lab behind GPT and ChatGPT.

Cognition AI$48bn
Artificial Intelligence. Valued at $48bn (September 2026).

Scale AI$29bnHiring
Data-centric infrastructure to accelerate the development of AI
Perplexity$20bnMafia
Answer engine that cites its sources.

Faire$12.6bnHiring
The global online platform empowering independent retail.
Claim this profile
Free and instant: prove you run confluence.sh and edit the profile yourself.
- Your logo, office address and founder photos
- The ✓ Verified mark next to Confluence Labs across the site
- Open roles listed on the Hiring board
- A followed link back to your website
A rank card with Confluence Labs's standing on Labspie, or a simple badge. Both link to this profile and update themselves.