San Francisco · updated 10 November 2026

AI research labs in San Francisco

5 research labs in San Francisco: 4 frontier and 1 bio and science. OpenAI is the best known.

  1. 1Frontier lab
  2. 2
    Anthropic logo
    AnthropicSafety-focused lab building the Claude models.Frontier lab
  3. 3
    Thinking Machines Lab logo
    Thinking Machines LabResearch and product lab for adaptable AI systems.Frontier lab
  4. 4
    Chan Zuckerberg Biohub logo
    Chan Zuckerberg BiohubNonprofit research network building virtual cell models.Bio and science lab
  5. 5
    Physical Intelligence logo
    Physical IntelligenceGeneral-purpose models for robots.Frontier lab

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How this list is ranked

By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.