Top AI startups in Boston
42 AI-native startups are based in Boston, 1 of them valued at $1bn or more. 17 were founded in the last three years.
- 1DataRobotArtificial intelligence. Valued at $6.3bn (July 2021).$6.3bn
- 2Maven BioLive intelligence for biopharma teams.Early stage
- 3BIOS HealthNeural interfaces to understand and use nerve data in medicine.Early stage
- 4CentaurWe Create Superior Data By Making Annotation CompetitiveGrowth
- 5PostEraMedicinal Chemistry powered by Machine LearningGrowth
- 6Ambi LabsAmerican software company based in Boston.Founded 2025
- 7Choate CatalystsBoston-based AI advisory firm.Founded 2023
- 8SmartAlphaUltrasound AI company.Founded 2019
- 9Yuma AIThe AI Support Agent for EcommerceEarly stage
- 10Alpha VantageDeveloper-friendly and enterprise-grade APIs for financial market…Early stage
- 11Perceptive TechnologiesAutomated tooth cutting for dentists using imaging, AI and roboticsGrowth
- 12Helix NanotechnologiesNext-generation mRNA platform to solve cancer, COVID and climate.Growth
- 131910Multimodal AI Platform for Modality Agnostic Drug Discovery™Growth
- 14DelineateAgents for Accelerated Clinical Trial DesignEarly stage
- 15Kernal BiologicsKernal is creating mRNA 2.0 therapies that work in specific cellsEarly stage
- 16Nextera Robotics | DIDGE.aiAI-native RoboticsEarly stage
- 17VectorAdvertising for the new internetEarly stage
- 18Arrow Intelligent SystemsSoftware company providing workflow automation for finance and compliance operations.Founded 2024
- 19Cooktop SafetyKitchen safety technology company.Founded 2021
- 20CreatioGlobal software company specializing in AI CRM, workflow automation and no-code development.Founded 2014
- 21UpsolveHelping low-income Americans overcome debt and rebuild credit at…Early stage
- 22Nabla BioWe use AI to design antibodies for intractable diseasesGrowth
- 23FlyCodeRecover failed subscription payments to increase retention and LTVEarly stage
- 24NuMindCreate custom NLP modelsEarly stage
- 25Brown FoodsMaking 'REAL' Cow and Human Milk!Early stage
- 26Expected ParrotSimulate your customers with AI agentsEarly stage
- 27Helios IntelligenceAt-home molecular body test: 1,000+ biomarkers from a drop of bloodEarly stage
- 28HYBRDcoaching agents for athletesEarly stage
- 29Pando BioscienceGen-AI Designed Enzymes for Pharmaceutical InnovationEarly stage
- 30UltrasoniumMetal manufacturing, faster, cheaper, and more versatile.Early stage
- 31Kino AIA video editor your team and coding agents work in togetherEarly stage
- 32AbInitio BioThe Intelligence layer for Drug ManufacturingEarly stage
- 33Boost RoboticsRobots for the inspection and maintenance of data centersEarly stage
- 34BramanteLife sciences reagents and softwareEarly stage
- 35InfraOptimalSelf optimizing dedicated inference endpointsEarly stage
- 36ReticularScaling Genomic AI for Embryo SelectionEarly stage
- 37RindlerThe IDE for TokenmaxxersEarly stage
- 38SenseiRobotic Training Data at ScaleEarly stage
- 39Vassar RoboticsGearless robot joints for better embodied AI.Early stage
- 40RiverbankInfrastructure CartographyEarly stage
- 41Dipole LabsAI-controlled optical switching for AI clustersEarly stage
- 42ZETA SURGICALNext-Generation Surgical Navigation and RoboticsEarly stage
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How this list is ranked
By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.