Top AI startups in Seattle
28 AI-native startups are based in Seattle, 1 of them valued at $1bn or more. 14 were founded in the last three years.
- 1StarcloudData centers in space$1.1bn

- 2AurelianAutomating non-emergency calls for 911 centersGrowth

- 3VetRecAI Scribe for veterinarians. Saving time and improving patient care.Early stage

- 4OptimlyAmerican AI brand optimization company.Founded 2025

- 5Sapient Technology GroupAmerican AI-native software company building production AI systems and multi-agent applications.Founded 2024

- 6WorknetSoftware company developing customer-facing AI agents for sales, success, and support.Founded 2021

- 7Axel TravelAI agent that saves you money on travelEarly stage

- 8Clearly AIAutomate security and privacy reviewsEarly stage

- 9IntunedCode-first scrapers and RPAs — built and maintained by AIEarly stage

- 10BoundaryThe programming language for AIEarly stage

- 11aSimcreate and share mini-apps with friendsEarly stage

- 12FeatherVoice AIEarly stage

- 13StracData Discovery, DLP, DSPM for SaaS, Cloud, Gen AI & EndpointsEarly stage

- 14adynThe first test designed to prevent birth control side effectsEarly stage

- 15Moonset HealthAI for Post-Acute Senior Care (Hospice, Home Health, Skilled Nursing…Early stage

- 16SilurianFoundation models to simulate Earth, starting with weather.Early stage

- 17Manifold FreightAggregating Spot Freight Opportunities for CarriersEarly stage

- 18TerrakottaAI platform for phone-first sellersEarly stage

- 19ChamberThe AIOps Agent for ML TeamsEarly stage

- 20Constellation SpaceAI operating system for mega-scale satellite networks. Early stage

- 21CopyCat AIAI for Commercial Insurance AgenciesEarly stage

- 22DecohereReal-time generative AIEarly stage

- 23Sota2Help business find and discover AI solutionsEarly stage

- 24LimnionTelemetry storage for the agentic era.Early stage

- 25TalcEvent extraction for Medical ResearchersEarly stage

- 26BackdropBuilding your AI coworkers for any team, workflow, or industry. Early stage

- 27HubbleAI-native retrieval engine for medical recordsEarly stage

- 28BluedoorAI for public records request fulfillmentEarly stage

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How this list is ranked
By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.