Palo Alto · updated 10 November 2026

Top AI startups in Palo Alto

11 AI-native startups are based in Palo Alto, 2 of them valued at $1bn or more. 2 were founded in the last three years.

  1. 1
    SandboxAQ logo
    SandboxAQQuantum technology, Artificial intelligence. Valued at $5.6bn (December 2024).$5.6bn
  2. 2$5.1bn
  3. 3
    Discovery Loop logo
    Discovery LoopUS based startup.Founded 2026
  4. 4
    Gaia Dynamics logo
    Gaia DynamicsAI-powered global trade compliance software company.Founded 2025
  5. 5
    Inflection AI logo
    Inflection AIEnterprise AI built on its own models.Founded 2022
  6. 6
    LigaData logo
    LigaDataAmerican enterprise data and AI software company.Founded 2014
  7. 7Founded 2022
  8. 8Founded 2022
  9. 9Founded 2017
  10. 10Founded 2020
  11. 11
    Inceptive logo
    InceptiveDeep learning to design RNA medicines.

Related lists

AI research labs in Palo AltoUnicorns in Palo AltoTop AI startups in San FranciscoTop AI startups in New York CityTop AI startups in SeattleTop AI startups in Los AngelesTop AI startups in BostonTop AI startups in Austin

How this list is ranked

By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.