Top AI startups in Los Angeles
56 AI-native startups are based in Los Angeles, 1 of them valued at $1bn or more. 26 were founded in the last three years.
- 1Relativity SpaceBuilding humanity’s multiplanetary future.$4.2bn

- 2Akido LabsRebuilding healthcare with AI at the coreEarly stage

- 3Panorama EducationImproving education for every student.Growth

- 4AbsurdThe production canvas for AI film teamsEarly stage

- 5MarqVisionIP operating software for brands and content companiesGrowth

- 6ZeitviewInspection software for renewable energy & sustainable infrastructureGrowth

- 7Keyframe LabsBring AI to life with the world's best interactive avatarsEarly stage

- 8FlowspaceThe operating system powering ecommerce fulfillmentGrowth

- 9PirrosAI Platform for Architects and EngineersEarly stage

- 10rct AIbuild AI NPCsGrowth

- 11AI GenesisAmerican artificial intelligence company specializing in autonomous AI agents for customer service.Founded 2024

- 12SignalWorksAI consulting and software development company in Los Angeles, California.Founded 2025

- 13SmartFocus.aiAI-powered virtual focus group platform.Founded 2025

- 14Treza LabsAI video generation company based in Los Angeles.Founded 2026

- 15MixerBoxAI Super-Apps to Live Easier | The anything anytime superapps…Early stage

- 16Serif HealthHealthcare Price Transparency APIs and Data ProductsEarly stage

- 17Impossible MetalsUnderwater robotic vehicles that collect battery metals responsiblyGrowth

- 18PlaiCreate, launch, and optimize Facebook ads and ads on 10+ platformsEarly stage

- 19Merlin AIAI powered ERP for ConstructionEarly stage

- 20DRESSXAI software company for fashion e-commerce.Founded 2020
- 21PractisAmerican company that develops AI-based sales training software.Founded 2019
- 22Wonder DynamicsAmerican VFX company.Founded 2016
- 23Epsilon3AI-Powered ERP, MES, and Test Software for Complex OperationsGrowth

- 24Ignition BenefitsThe AI-Native Benefits BrokerageEarly stage

- 25Sorting RoboticsWe create automation technology for the cannabis industry.Early stage

- 26ScanbaseThe API for Diagnostic Test Analysis (COVID-19, FLU, RSV, STD,…Early stage

- 27OdaAI Agent for Home DesignEarly stage

- 28goodfinBuilding the next generation of wealthEarly stage

- 29YonduRobots to Automate FulfillmentEarly stage

- 30MindFortAutonomous Security SwarmsEarly stage

- 31VokerThe Agent Analytics PlatformEarly stage

- 32MochiWatch and create animeEarly stage

- 33SuperunitFaster, more profitable background checks with AIEarly stage

- 34TryNearbyLocal creators for local businessesEarly stage

- 35AnythingLLMThe open-source AI platform enterprises run on their own hardwareEarly stage

- 36ArtifactAn Collaborative, AI-native IDE for Hardware EngineersEarly stage

- 37MassdriverInternal developer platform for Terraform, OpenTofu and HelmEarly stage

- 38StreamablePowering the biggest IRL streamers today.Early stage

- 39Cognitio LabsAI back office for food product quality teamsEarly stage

- 40LFcarryMarketplace for game boosting, carries and coachingEarly stage

- 41PARES AIAI-native real estate services firmEarly stage

- 42WavedashPlay the latest games in your browser with no downloadsEarly stage

- 43AI Tech PacksBuild factory ready tech packs in minutes.Early stage

- 44Alt-XBuilding the best venue for private markets exposure.Early stage

- 45AtmetoBuilding a frontier world model for powerEarly stage

- 46EndstackThe complete, collaborative workspace for humans and agentsEarly stage

- 47ForerunnerQuick-turn bent tube shop for aerospace, energy, industrialsEarly stage

- 48GrocaloAI brain for creators that runs their social contentEarly stage

- 49HellometerMaking fast food fasterEarly stage

- 50IMPACT DronesAir Defense as a Service for Civilian Infrastructure.Early stage

The top 50 of 56. Everything else is on the Los Angeles page.
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How this list is ranked
By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.